New research reveals that trait shyness is linked to reduced spontaneous neural activity in the cerebellum, a brain region traditionally associated with motor control but increasingly recognized for its role in emotion and social cognition. Using resting-state fMRI and ReHo analysis, researchers found that shy individuals exhibited lower synchrony in the cerebellar Crus I region.

A new study shows that humans possess a form of “remote touch,” allowing them to detect hidden objects in sand before making direct contact. Participants sensed buried cubes by perceiving tiny mechanical reflections generated as they moved their fingertips through the sand.

A new study shows that CBD delivered through a nano-micelle system can cross the blood–brain barrier and produce rapid neuropathic pain relief. The formulation, called CBD-IN, helped mice within 30 minutes and avoided the motor and cognitive side effects often seen with conventional pain drugs.

Researchers have shown that adaptive music systems that adjust tempo and rhythm to match a user’s movement can make exercise significantly more enjoyable and motivating. These personalized interactive music systems use real-time data from wearables to keep music aligned with walking, cycling, or weightlifting intensity, helping users stay in rhythm and maintain effort.

A new imagery-focused therapy called iMAPS may help people with psychosis gain control over disturbing mental images that fuel paranoia, fear, and hallucinations. In a feasibility trial of 45 participants, the approach showed strong patient engagement and meaningful reductions in distress by teaching individuals to understand, transform, and re-script intrusive images.

A new study examining real-world hospital data reveals early indicators of who is most likely to benefit from Cobenfy, the first new schizophrenia drug mechanism approved in 50 years. Patients with strong negative symptoms responded best to the xanomeline–trospium combination, showing notable improvements in social behavior and mood.

Researchers have identified a previously unknown “hook-like” domain in the tail of the kinesin-2 motor protein that explains how these molecular machines select the right cargo inside cells. Using cryo-electron microscopy and simulations, the team mapped the HAC domain’s atomic structure and showed how it binds both adaptor proteins and cargo, forming a highly specific recognition interface.

A week-long retreat combining meditation and mind-body healing produced significant changes in brain activity and blood biology, demonstrating how consciousness-based practices can transform physical health. Participants showed reduced default-mode activity, enhanced neural connectivity, elevated natural opioids, immune activation, and metabolic shifts—effects that extended beyond the brain into the entire body.

Scientists have created an advanced visual neuroprosthesis that communicates bidirectionally with the brain, marking one of the biggest steps yet toward restoring functional vision. Unlike earlier devices, this closed-loop implant adapts in real time to neural activity, allowing the system and the brain to “learn” from each other.

A new study shows that oxidative stress—an imbalance between damaging molecules and antioxidants—may contribute to repetitive behaviors observed in mice, similar to those seen in autism spectrum disorder and schizophrenia. Researchers found that higher levels of oxidative stress biomarkers, including glutathione and specific proteins, were linked to more severe stereotypies in young mice.

A new study reveals that aggression and self-harm share a biological foundation in the brain’s response to early-life trauma. Researchers discovered that trauma increases activity in calcium channels within a neural circuit connecting the nucleus reuniens and hippocampus, amplifying pain processing and impulsive behavior.

Researchers found that living in a socioeconomically deprived neighborhood can harm brain health as early as midlife. People from these areas showed more signs of small-vessel brain damage, slower thinking skills, and poorer control of lifestyle factors such as blood pressure, obesity, and sleep.